remedium bio

Remedium Bio is a Boston based gene therapy company focused on the development of highly innovative treatments for a broad range of diseases. The Remedium approach utilizes proven scientific fundamentals, in a novel way, to treat the most debilitating conditions. Our leading candidates include a gene therapy treatment for Osteoarthritis, delivered via an intrinsically safe Adeno-Associated Viral (AAV) vector, a treatment to alleviate hyperglycemia in Type 1 and Type 2 Diabetes, and a gene therapy product to improve long term survival post Myocardial Infarction.

treatment modalities

  • Cardiology
    Myocardial Infarction

    Cardiovascular disease is the leading cause of death in the world and many developed and developing countries. With over 1.5 M annual cases of myocardial infarction in the US alone, and a nearly 25% - 1 year and over 50% - 2 year mortality rates despite availability of a broad range of efficacious treatment options, the disease remains the most debilitating condition facing mankind in the modern era. Remedium’s unique gene therapy approach utilizes proven therapeutic targets to tilt the landscape toward longer-term survival, in favor of the patient.

  • Endocrinology
    Diabetes

    Type 1 Diabetes is a metabolic disorder caused predominantly by beta-cell insufficiency. In the case of insulin-dependent diabetes mellitus, beta-cells are lost as a result of an autoimmune response eventually causing endocrine dysregulation. Current therapies include lifelong insulin replacement, while several investigational approaches attempt to replace beta-cells with protective exterior barriers. The Remedium approach utilizes genetic engineering and a clinically-proven delivery system, to prevent the most debilitating effect of Type 1 Diabetes - persistent hyperglycemia, helping patients keep sugar levels under control throughout the day.

  • Hematology
    Circulating Enzyme Deficiency

    A number of genetic and acquired diseases of blood arise from inactivating mutations or insufficiencies of circulating proteins; most notably globulins and complement system proteins. Several of these proteins have been demonstrated to decline with age, potentially resulting in increased risk of developing opportunistic infections and autoimmune diseases. Remedium’s platform technology is uniquely positioned to augment or replace the function of specific hematological components to prevent overt pathology.

  • Rheumatology
    Osteoarthritis

    Symptomatic Osteoarthritis (OA) is a disease of the joints that results in progressive degeneration of cartilage. While both genetic and environmental factors have been implicated in the severity and rate of progression, the most strongly correlated factor with disease severity is age. OA is the most common rheumatic disorder with a prevalence of 10-13% among men and women over the age of 60. With only a few currently approved disease moderating treatments, there is currently no approved therapy that can reverse progression of OA and restore cartilage thickness. Remedium Bio is developing a single injection, intrinsically safe, gene therapy, based on a well characterized AAV2 vector and gene of interest.

REMEDIUM PIPELINE

The Remedium Bio pipeline consists of a broad range of therapies for immune and age related conditions. The treatment modalities are founded in proven scientific fundamentals and focused on therapeutic treatments using a novel approach.

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Background

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proven fundamentals

Remedium therapies are based on proven fundamental components including clinically validated targets, commercial delivery vectors, and time-tested manufacturing technologies.

novel approach

The technology is then applied to treating disease using a fundamentally novel, patent pending approach. An approach, uniquely matched specifically with the target condition.

Infinite Potential

Each technology serves as a potential platform, from treating conditions resulting from age related decline, to replacing extracellular proteins in a safe and adjustable way.

Get In Touch

We are always interested in starting a new conversation and are looking forward to hearing from you. Thank you in advance for your inquiry and please have a wonderful day!


1116 Great Plain Ave, Suite 203                        
Needham, MA                        
02492


E: info@remedium-bio.com 
P: +1 (978) 467 5217